Dysplastic nevus - Nevus Dysplastic
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Dysplastic nevi ― Thathas a’ moladh biopsy dha muinntir an Iar.
References
Tha Dysplastic nevus , ris an canar cuideachd neo-àbhaisteach no Clarks nevus, air deasbadan a bhrosnachadh ann an dermatology agus dermatopathology. Bidh dotairean gu tric a’ biopsy na mòlan sin oir faodaidh iad coimhead neo-àbhaisteach agus draghan a thogail mu mhelanoma.
A dysplastic nevus is also referred to as an atypical or Clarks nevus and has been the topic of much debate in the fields of dermatology and dermatopathology. It is an acquired mole demonstrating a unique clinical and histopathologic appearance that sets it apart from the common nevus. These moles appear atypical clinically, often with a fried-egg appearance, and are commonly biopsied by providers due to the concern for melanoma.
A dysplastic nevus is also referred to as an atypical or Clarks nevus and has been the topic of much debate in the fields of dermatology and dermatopathology. It is an acquired mole demonstrating a unique clinical and histopathologic appearance that sets it apart from the common nevus. These moles appear atypical clinically, often with a fried-egg appearance, and are commonly biopsied by providers due to the concern for melanoma.
Faodaidh Dysplastic nevi , ris an canar cuideachd neo-àbhaisteach no Clark nevi, leantainn gu melanoma uaireannan. Tha timcheall air 36% de melanomas rim faighinn faisg air dysplastic nevi. Tha comharran gum faodadh nevus dysplastic tionndadh gu melanoma a’ toirt a-steach cumadh neo-chòmhnard, barrachd atharrachaidhean pigment, no dath liath-ghlas. Mar as trice bidh na cansearan sin a’ tachairt aig aois nas òige (timcheall air meadhan nan tritheadan) , faodaidh iad a bhith iomadach, agus gu tric bidh iad air an stoc. Gu ginteil, tha dysplastic nevi eadar nevi neo-àbhaisteach agus melanoma. Ach, chan eil ach 20% gu 30% de melanomas a’ tighinn bho nevi a th’ ann mar-thà. Leis nach eil a’ mhòr-chuid de nevi a’ fàs mar melanoma, mar as trice chan eilear a’ moladh an toirt air falbh le casg.
Dysplastic nevus, also called atypical or Clark nevus, can be precursor to melanoma, as the observation that 36% of melanomas have dysplastic nevi near the invasive tumor supports. Signs that a dysplastic nevus may have transitioned into a melanoma include asymmetry in contour, a noticeable increase in pigment variations, or a grayish tint indicating regression. These malignancies typically arise at a younger age (mid-thirties), are sometimes multiple, and are often found on the trunk. Molecularly, dysplastic nevi have a profile intermediate between benign nevi and malignant melanoma. While there is a recognized connection between dysplastic nevi and melanoma, it’s crucial to note that only about 20% to 30% of melanomas evolve from preexisting nevi. Given that the majority of dysplastic and typical nevi do not develop into melanoma, preventive removal of melanocytic nevi is not typically advised.
Dysplastic nevus, also called atypical or Clark nevus, can be precursor to melanoma, as the observation that 36% of melanomas have dysplastic nevi near the invasive tumor supports. Signs that a dysplastic nevus may have transitioned into a melanoma include asymmetry in contour, a noticeable increase in pigment variations, or a grayish tint indicating regression. These malignancies typically arise at a younger age (mid-thirties), are sometimes multiple, and are often found on the trunk. Molecularly, dysplastic nevi have a profile intermediate between benign nevi and malignant melanoma. While there is a recognized connection between dysplastic nevi and melanoma, it’s crucial to note that only about 20% to 30% of melanomas evolve from preexisting nevi. Given that the majority of dysplastic and typical nevi do not develop into melanoma, preventive removal of melanocytic nevi is not typically advised.
Is e seòrsa de tumhair a th’ ann am melanoma a bhios a’ cruthachadh nuair a dh’fhàsas melanocytes, ceallan le uallach airson dath craiceann, aillse. Tha melanocytes a 'tighinn bhon suaicheantas neural. Tha seo a’ ciallachadh gum faod melanomas leasachadh chan ann a-mhàin air a’ chraiceann ach cuideachd ann an raointean eile far a bheil ceallan suaicheantas neural a’ gluasad, leithid an t-slighe gastrointestinal agus an eanchainn. Tha an ìre mairsinn airson euslaintich le melanoma tràth-ìre (ìre 0) àrd aig 97%, fhad ‘s a tha e a’ tuiteam gu mòr gu timcheall air 10% dhaibhsan a chaidh a dhearbhadh le galar ìre adhartach (ìre IV) .
A melanoma is a tumor produced by the malignant transformation of melanocytes. Melanocytes are derived from the neural crest; consequently, melanomas, although they usually occur on the skin, can arise in other locations where neural crest cells migrate, such as the gastrointestinal tract and brain. The five-year relative survival rate for patients with stage 0 melanoma is 97%, compared with about 10% for those with stage IV disease.
A melanoma is a tumor produced by the malignant transformation of melanocytes. Melanocytes are derived from the neural crest; consequently, melanomas, although they usually occur on the skin, can arise in other locations where neural crest cells migrate, such as the gastrointestinal tract and brain. The five-year relative survival rate for patients with stage 0 melanoma is 97%, compared with about 10% for those with stage IV disease.
○ Cunnart aillse
Mar a chithear ann an daoine Caucasian anns na Stàitean Aonaichte, tha an fheadhainn le dysplastic nevi ann an cunnart fad beatha melanoma nas àirde na 10%. Air an làimh eile, tha an fheadhainn aig nach eil nevus dysplastic ann an cunnart melanoma nas lugha na 1%.
○ Precaution airson daoine fa leth le dysplastic nevi
Mar as trice thathar a ‘moladh fèin-sgrùdadh craiceann airson casg a chuir air melanoma (le bhith a’ comharrachadh nevi neo-àbhaisteach a dh’ fhaodar a thoirt air falbh) no airson lorg tràth air tumhan a tha ann mar-thà. Bu chòir do dhaoine le eachdraidh pearsanta no teaghlaich de aillse craiceann no de nevi ioma-neo-àbhaisteach dermatologist fhaicinn co-dhiù aon uair sa bhliadhna gus a bhith cinnteach nach eil iad a’ leasachadh melanoma.
Tha an giorrachadh [ABCDE] air a bhith feumail airson solaraichean cùram slàinte agus daoine neo-chliùiteach a chuideachadh a’ cuimhneachadh air prìomh fheartan melanoma. Gu mì-fhortanach airson an neach cuibheasach, faodaidh feartan [ABCDE] a bhith aig mòran de keratoses seborrheic, cuid de lentigo senilis, agus eadhon warts, agus chan urrainnear a bhith eadar-dhealaichte bho melanoma.
○ [ABCDE]
Asymmetrical: lesion craiceann neo-chunbhalach.
Border: Tha crìoch an lesion neo-riaghailteach.
Color: mar as trice bidh grunn dhathan neo-riaghailteach aig melanomas.
Diameter: tha nevi nas motha na 6 mm nas buailtiche a bhith nan melanomas na nevi nas lugha.
Evolution: Faodaidh mean-fhàs (ie atharrachadh) nevus no lesion nochdadh gu bheil an lesion a’ fàs malignant.